The ZIWR was founded in January 2002 within the Jacob Blaustein Institutes for Desert Research, at the Sede Boqer Campus of Ben-Gurion University of the Negev. ZIWR scientists use experimental and theoretical approaches to conduct fundamental water related research to understand wide-ranging phenomena. Our broad-based research encompasses nanoscience and pore scale phenomena, and extends to pilot projects and field studies. Our interdisciplinary team includes hydrologists, soil scientists, geologists, chemists, microbiologists, and engineers. The result is a unique scientific environment facilitating the investigation of environmental challenges and the development of engineering solutions for water-related problems. Young and dynamic, the Zuckerberg Institute for Water Research is open to change, and research topics are “fine-tuned” to remain responsive to constantly evolving needs and challenges. The ZIWR vision is to be a leading international multidisciplinary institute studying water in the anthropogenic and natural spheres, and a national center of expertise and training in water issues. In its research and education activities, the ZIWR will identify current and emerging fundamental and applied challenges in water-related developments, rehabilitation, and stewardship.